Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl–Coenzyme A Reductase Inhibitor FR901512 | Zendy

Hiroya Itoh | Zendy; Makoto Matsui | Zendy; Toshitaka Kumagai | Zendy; Masanori Arita | Zendy; Masayuki Machida | Zendy; Takahiro Shibata | Zendy

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Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl–Coenzyme A Reductase Inhibitor FR901512

Author(s) -

Hiroya Itoh,

Makoto Matsui,

Toshitaka Kumagai,

Masanori Arita,

Masayuki Machida,

Takahiro Shibata

Publication year - 2017

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00129-17

Subject(s) - whole genome sequencing , strain (injury) , reductase , coenzyme a , biology , sequence (biology) , genome , genetics , computational biology , gene , biochemistry , enzyme , anatomy

Fungal strain 14919 was originally isolated from a soil sample collected at Mt. Kiyosumi, Chiba Prefecture, Japan. It produces FR901512, a potent and strong 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The genome sequence of fungal strain 14919 was determined and annotated to improve the productivity of FR901512.

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