Open AccessGenome Sequence and Annotation of Helicobacter pylori Strain Hp238, Isolated from a Taiwanese Patient with Mucosa-Associated Lymphoid Tissue Lymphoma
Author(s) -
Cheng-Yen Kao,
Jenn-Wei Chen,
Yi Huang,
Shew-Meei Sheu,
BorShyang Sheu,
Jiunn-Jong Wu
Publication year - 2015
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00006-15
Subject(s) - helicobacter pylori , biology , lymphoma , whole genome sequencing , strain (injury) , lymphatic system , genome , malt lymphoma , gastric mucosa , pathogenesis , internalization , gene , genetics , immunology , stomach , cell , anatomy , biochemistry
We present the complete genome sequence of Helicobacter pylori strain Hp238, isolated from a Taiwanese patient with gastric mucosa-associated lymphoid tissue lymphoma. Importantly, H. pylori strain Hp238 can multiply in THP-1 cells after internalization through the induction of autophagosome formation. These genome data will help to identify genes associated with H. pylori intracellular multiplication and pathogenesis.