
Rearranged Subtelomeric rRNA Genes in Giardia duodenalis
Author(s) -
Jacqueline Upcroft,
Mahin Abedinia,
Peter Upcroft
Publication year - 2005
Publication title -
eukaryotic cell
Language(s) - English
Resource type - Journals
eISSN - 1535-9778
pISSN - 1535-9786
DOI - 10.1128/ec.4.2.484-486.2005
Subject(s) - subtelomere , biology , giardia , gene , genetics , ribosomal rna , chromosome , telomere , microbiology and biotechnology
Giardia duodenalis has linear chromosomes capped with typical eukaryotic repeats [(TAGGG)n], subtelomeric rRNA genes, and telomere gene units. The absence of two closely associated NotI sites in the large-subunit rRNA gene was used as an indicator in hybridizations of one- and two-dimensional NotI-cleaved Giardia chromosome separations that some chromosomes carry only rearranged and, by deduction, nonfunctional rRNA genes.