Open AccessSynthesis of Chloroplast Galactolipids in Apicomplexan Parasites
Author(s) -
Éric Maréchal,
Nahid Azzouz,
Cristiana Santos de Macedo,
Maryse A. Block,
Jean E. Feagin,
Ralph Τ. Schwarz,
Jacques Joyard
Publication year - 2002
Publication title -
eukaryotic cell
Language(s) - English
Resource type - Journals
eISSN - 1535-9778
pISSN - 1535-9786
DOI - 10.1128/ec.1.4.653-656.2002
Subject(s) - apicoplast , biology , galactolipids , plastid , chloroplast , plasmodium falciparum , glycan , biochemistry , algae , glycolipid , dinoflagellate , toxoplasma gondii , botany , gene , genetics , glycoprotein , malaria , antibody , immunology
Monogalactosyldiacylglycerol and digalactosyldiacylglycerol are major chloroplast lipids of algae and land plants and are synthesized within the plastid envelope. Here we report that in Toxoplasma gondii and Plasmodium falciparum lysates, radiolabeled UDP-galactose is incorporated into monogalactosylcerebrosides, monogalactosyldiacylglycerol, and digalactosyldiacylglycerol due to distinct enzymological activities. Furthermore, DGDG is immunologically detected in apicomplexans.