Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family | Zendy

Loubna Youssar | Zendy; Björn Grüning | Zendy; Anika Erxleben | Zendy; Stefan Günther | Zendy; Wolfgang Hüttel | Zendy

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Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family

Author(s) -

Loubna Youssar,

Björn Grüning,

Anika Erxleben,

Stefan Günther,

Wolfgang Hüttel

Publication year - 2012

Publication title -

eukaryotic cell

Language(s) - English

Resource type - Journals

eISSN - 1535-9778

pISSN - 1535-9786

DOI - 10.1128/ec.05302-11

Subject(s) - biology , genome , genetics , sequence (biology) , whole genome sequencing , fungus , computational biology , genome evolution , gene , botany

The anamorphic fungusGlarea lozoyensis mutant strain 74030 is an overproducer of pneumocandin B0 , which is chemically converted into Cancidas, a potent antibiotic against clinically important fungal pathogens. Pneumocandins are acylated, cyclic hexapeptides with unusual hydroxylated amino acids. With theGlarea lozoyensis genome, the first species from the large polyphyletic familyHelotiaceae has been sequenced.

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