Primary and Probable Secondary Dengue Virus (DV) Infection Rates in Relation to Age among DV IgM-Positive Patients Residing in the United States Mainland Versus the Caribbean Islands | Zendy

Harry E. Prince | Zendy; Cindy Yeh | Zendy; Mary Lapé-Nixon | Zendy

Open Access

Primary and Probable Secondary Dengue Virus (DV) Infection Rates in Relation to Age among DV IgM-Positive Patients Residing in the United States Mainland Versus the Caribbean Islands

Author(s) -

Harry E. Prince,

Cindy Yeh,

Mary Lapé-Nixon

Publication year - 2011

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.05519-11

Subject(s) - dengue fever , dengue virus , virology , mainland china , immunoglobulin m , mainland , caribbean region , demography , medicine , geography , immunology , biology , antibody , immunoglobulin g , political science , ecology , archaeology , sociology , china , law , latin americans

Dengue virus (DV) primary infection and probable secondary infection rates in relation to patient age (years) were determined for DV IgM-positive U.S. mainland residents (presumed travelers to areas of DV endemicity) and Caribbean island (area of DV endemicity) residents by evaluating IgG status and IgG avidity. Regardless of place of residence, most patients ≤20 years old exhibited primary infection and most patients >60 years old exhibited probable secondary infection. Among patients 21 to 60 years old, the primary infection rate was markedly higher in U.S. residents.

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