Comparison of Galactomannan Enzyme Immunoassay Performance Levels when Testing Serum and Plasma Samples | Zendy

P. Lewis White | Zendy; Tim Jones | Zendy; Katie Whittle | Zendy; Joanne Watkins | Zendy; Rosemary A. Barnes | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Comparison of Galactomannan Enzyme Immunoassay Performance Levels when Testing Serum and Plasma Samples

Author(s) -

P. Lewis White,

Tim Jones,

Katie Whittle,

Joanne Watkins,

Rosemary A. Barnes

Publication year - 2013

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00730-12

Subject(s) - galactomannan , immunoassay , enzyme , chromatography , medicine , chemistry , immunology , antibody , biochemistry , aspergillosis

Diagnostic galactomannan (GM) enzyme immunoassay (EIA) testing is formally validated only for serum, though in practice, plasma is occasionally tested. It is assumed, but not confirmed, that results will be comparable to those for serum. GM EIA when testing plasma was evaluated, providing sensitivity (85.7%) and specificity (85.4%) comparable to those for serum. Plasma index values were higher than those for serum; if plasma GM EIA were used to define probable cases, four additional cases would have been diagnosed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research