Persistence of Leishmania donovani Antibodies in Past Visceral Leishmaniasis Cases in India
Author(s) -
Kamlesh Gidwani,
Albert Picado,
Bart Ostyn,
Shri Prakash Singh,
Rajiv Kumar,
Basudha Khanal,
Veerle Lejon,
François Chappuis,
Marleen Boelaert,
Shyam Sundar
Publication year - 2010
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00473-10
Subject(s) - leishmania donovani , visceral leishmaniasis , direct agglutination test , persistence (discontinuity) , leishmaniasis , antibody , titer , immunology , virology , leishmania , antibody titer , medicine , biology , serology , parasite hosting , geotechnical engineering , world wide web , computer science , engineering
The persistence of anti-Leishmania donovani antibodies in past visceral leishmaniasis (VL) cases was retrospectively assessed by means of the direct agglutination test (DAT) and the rK39 enzyme-linked immunosorbent assay (ELISA). Antibody titers remained high for an extended period of time in past cases of VL. These results highlight the need to carefully elicit the history of patients with VL symptoms.
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