Potential Use of the Hemagglutinin-Neuraminidase Glycoprotein of Newcastle Disease Virus Expressed in Rachiplusia nu Larvae as an Immunogen for Chickens | Zendy

Silvina Chimeno Zoth | Zendy; Evangelina Gómez | Zendy; Juan Manuel Carballeda | Zendy; Oscar Taboga | Zendy; Elisa Carrillo | Zendy; Analía Berinstein | Zendy

Open Access

Potential Use of the Hemagglutinin-Neuraminidase Glycoprotein of Newcastle Disease Virus Expressed in Rachiplusia nu Larvae as an Immunogen for Chickens

Author(s) -

Silvina Chimeno Zoth,

Evangelina Gómez,

Juan Manuel Carballeda,

Oscar Taboga,

Elisa Carrillo,

Analía Berinstein

Publication year - 2009

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00432-08

Subject(s) - immunogen , virology , newcastle disease , hemagglutinin (influenza) , biology , virus , glycoprotein , neuraminidase , recombinant dna , antibody , antigen , microbiology and biotechnology , monoclonal antibody , immunology , biochemistry , gene

The hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus (NDV) was obtained as a recombinant antigen inRachiplusia nu larvae. When it was used as an immunogen in chickens, a solid immune response, including neutralizing antibodies, was detected, demonstrating the potential use of this simple and economic strategy in the design of recombinant anti-NDV vaccines.

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