Open AccessCompartmentalization of Interleukin-6 Response in a Patient with Septic Meningococcal Peritonitis
Author(s) -
Alexandre Leite de Souza,
Jaques Sztajnbok,
Maristela Marques Salgado,
Carla Cristina Romano,
Maria das Graças Adelino Alkmin,
Alberto José da Silva Duarte,
Antônio Carlos Seguro
Publication year - 2006
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00269-06
Subject(s) - peritonitis , medicine , compartmentalization (fire protection) , neisseria meningitidis , peritoneal fluid , pathogenesis , immunology , meningococcal disease , interleukin , microbiology and biotechnology , cytokine , biology , bacteria , biochemistry , genetics , enzyme
We report the first case ofNeisseria meningitidis -induced septic peritonitis diagnosed by PCR assay of peritoneal fluid. Concentrations of interleukin-6 were notably higher in the peritoneal fluid than in the blood. PCR diagnosis of septic meningococcal peritonitis and the pathogenesis of the disease are discussed.