Performance of the Epstein-Barr Virus and Herpes Simplex Virus Immunoglobulin M Assays on the Liaison Platform with Sera from Patients Displaying Acute Parvovirus B19 Infection | Zendy

Elisa Costa | Zendy; Nuria Tormo | Zendy; María Ángeles Clari | Zendy; Dayana Bravo | Zendy; Beatriz MuñozCobo | Zendy; David Navarro | Zendy

Open Access

Performance of the Epstein-Barr Virus and Herpes Simplex Virus Immunoglobulin M Assays on the Liaison Platform with Sera from Patients Displaying Acute Parvovirus B19 Infection

Author(s) -

Elisa Costa,

Nuria Tormo,

María Ángeles Clari,

Dayana Bravo,

Beatriz MuñozCobo,

David Navarro

Publication year - 2009

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00142-09

Subject(s) - parvovirus , herpes simplex virus , virology , antibody , virus , immunoglobulin m , epstein–barr virus , medicine , immunology , immunoglobulin g , herpesviridae , epstein–barr virus infection , biology , viral disease

Acute parvovirus B19 infection has been reported to cause false-positive results frequently in the Epstein-Barr (EBV) and herpes simplex virus (HSV) immunoglobulin M (IgM) assays from DiaSorin performed on the Liaison platform. We tested 65 sera from patients with a presumptive or conclusive diagnosis of acute parvovirus B19 infection in both assays and obtained no false-positive results in the EBV IgM test and 10.4% nonspecific reactivities in the HSV IgM assay. Our data support the specificity of both assays in this clinical setting.

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