Disappearance of Vaccine-Type Invasive Pneumococcal Disease and Emergence of Serotype 19A in a Minority Population with a High Prevalence of Human Immunodeficiency Virus and Low Childhood Immunization Rates | Zendy

Azadeh Tasslimi | Zendy; Erica J. Sison | Zendy; Elizabeth StoryRoller | Zendy; David Alland | Zendy; Michele Burday | Zendy; Susan Morrison | Zendy; Sandhya Nalmas | Zendy; Stephen W. Smith | Zendy; P. Thomas | Zendy; Peter Wenger | Zendy; Anushua Sinha | Zendy

Open Access

Disappearance of Vaccine-Type Invasive Pneumococcal Disease and Emergence of Serotype 19A in a Minority Population with a High Prevalence of Human Immunodeficiency Virus and Low Childhood Immunization Rates

Author(s) -

Azadeh Tasslimi,

Erica J. Sison,

Elizabeth StoryRoller,

David Alland,

Michele Burday,

Susan Morrison,

Sandhya Nalmas,

Stephen W. Smith,

P. Thomas,

Peter Wenger,

Anushua Sinha

Publication year - 2009

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00140-09

Subject(s) - immunization , pneumococcal disease , serotype , pneumococcal vaccine , medicine , virology , population , epidemiology , disease , immunology , streptococcus pneumoniae , biology , environmental health , antibody , microbiology and biotechnology , antibiotics

We analyzed the epidemiology of invasive pneumococcal disease (IPD) following introduction of pneumococcal conjugated vaccine in an urban population with a 2% human immunodeficiency virus (HIV) prevalence and history of low childhood immunization rates. We observed near-elimination of vaccine-type IPD. Substantial disease remains due to non-vaccine-type pneumococci, highlighting the need to increase pneumococcal immunization among HIV-infected adults.

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