Open AccessOccurrence of Immunoglobulin M Antibodies against Several Bacterial and Viral Pathogens in Acute Hantavirus Infection
Author(s) -
Nele Wellinghausen,
Andrea Goetz,
Ursula Weber
Publication year - 2012
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00109-12
Subject(s) - hantavirus , antibody , hantavirus infection , virology , immunoglobulin m , immunoglobulin g , immunology , biology , microbiology and biotechnology , medicine , virus
Elevated levels of immunoglobulin M antibodies against various pathogens, most frequently Epstein-Barr-virus andCoxiella burnetii , were detected by immunoassay in 15 of 48 patients (31.3%) with acute Puumala virus infections. Although the mechanisms leading to this IgM response are not clear yet, polyspecific immunoglobulin M antibodies have to be taken into account to avoid misinterpretation of serological results in acute hantavirus infection.