Open AccessDevelopment and Characterization of Mouse Models of Infection with Aerosolized Brucella melitensis and Brucella suis
Author(s) -
Sophie J. Smither,
Stephanie D. Perkins,
Cheryl M. Davies,
Anthony J. Stagg,
Michelle Nelson,
Helen S. Atkins
Publication year - 2009
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cvi.00029-09
Subject(s) - brucella melitensis , brucella , aerosolization , virology , brucellosis , microbiology and biotechnology , brucella suis , biology , anatomy , inhalation
There is a need to identify vaccines that can protect againstBrucella , a potential bioterrorism agent. We have developed mouse models of infection with aerosolizedBrucella melitensis andBrucella suis and demonstrated their utility for the evaluation of vaccines using the model liveB. melitensis vaccine strain Rev.1.