Use of Protein-Specific Monoclonal Antibody-Based Latex Agglutination for Rapid Diagnosis of Burkholderia pseudomallei Infection in Patients with Community-Acquired Septicemia | Zendy

Pattama Ekpo | Zendy; Utane Rungpanich | Zendy; Supinya Pongsunk | Zendy; Pimjai Naigowit | Zendy; Vimon Petkanchanapong | Zendy

Open Access

Use of Protein-Specific Monoclonal Antibody-Based Latex Agglutination for Rapid Diagnosis of Burkholderia pseudomallei Infection in Patients with Community-Acquired Septicemia

Author(s) -

Pattama Ekpo,

Utane Rungpanich,

Supinya Pongsunk,

Pimjai Naigowit,

Vimon Petkanchanapong

Publication year - 2007

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00011-07

Subject(s) - burkholderia pseudomallei , latex fixation test , melioidosis , microbiology and biotechnology , burkholderia , monoclonal antibody , blood culture , direct agglutination test , agglutination (biology) , antibody , monoclonal , medicine , sepsis , immunology , biology , bacteria , serology , antibiotics , genetics

A latex agglutination test employing monoclonal antibody specific to a 30-kDa protein ofBurkholderia pseudomallei was used to detect the organisms in blood culture specimens from 1,139 patients with community-acquired septicemia. The sensitivity, specificity, and positive and negative predictive values of the test were 96.75%, 99.61%, 96.75%, and 99.61%, respectively.

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