Immunoglobulin G Avidities in Infants in Mexico after Primary Immunization with Three Doses of Polyribosylribitol Phosphate-Tetanus ToxoidHaemophilus influenzaeType b Vaccine | Zendy

Patricia Gomez-de-León | Zendy; Francisco Javier DíazGarcía | Zendy; Alberto VillaseñorSierra | Zendy; J Segura | Zendy; Martha I. Carranza | Zendy; José Luis Arredondo-Garcı́a | Zendy; José Ignacio Santos | Zendy

Open Access

Immunoglobulin G Avidities in Infants in Mexico after Primary Immunization with Three Doses of Polyribosylribitol Phosphate-Tetanus ToxoidHaemophilus influenzaeType b Vaccine

Author(s) -

Patricia Gomez-de-León,

Francisco Javier DíazGarcía,

Alberto VillaseñorSierra,

J Segura,

Martha I. Carranza,

José Luis Arredondo-Garcı́a,

José Ignacio Santos

Publication year - 2008

Publication title -

clinical and vaccine immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.649

H-Index - 77

eISSN - 1556-6811

pISSN - 1556-679X

DOI - 10.1128/cvi.00009-08

Subject(s) - tetanus , toxoid , hib vaccine , diphtheria , vaccination , haemophilus influenzae , immunization , medicine , antibody , haemophilus , immunoglobulin g , immunology , virology , microbiology and biotechnology , biology , conjugate vaccine , bacteria , antibiotics , genetics

Serum immunoglobulin G concentrations and avidities specific toHaemophilus influenzae type b (Hib) were measured in 208 children living in Guadalajara and Mexico City. Protective concentrations were found in 98.9% and 100.0% of participants, respectively. Geometric mean concentrations differed between both populations and/or among age groups. Mean avidities differed only among the 7- to 12-month-old children. Diphtheria-tetanus-whole-cell pertussis-hepatitis B-Hib primary vaccination seems to induce protection in Mexican children.

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