Open AccessPlasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Author(s) -
Xinzhuan Su,
Kristin D. Lane,
Lu Xia,
Juliana M. Sá,
Thomas E. Wellems
Publication year - 2019
Publication title -
clinical microbiology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.177
H-Index - 282
eISSN - 1070-6305
pISSN - 0893-8512
DOI - 10.1128/cmr.00019-19
Subject(s) - malaria , genomics , drug resistance , biology , genetics , plasmodium falciparum , epidemiology , computational biology , virology , genome , medicine , gene , immunology , pathology
ProtozoanPlasmodium parasites are the causative agents of malaria, a deadly disease that continues to afflict hundreds of millions of people every year. Infections with malaria parasites can be asymptomatic, with mild or severe symptoms, or fatal, depending on many factors such as parasite virulence and host immune status. Malaria can be treated with various drugs, with artemisinin-based combination therapies (ACTs) being the first-line choice.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom