Open AccessComparison of Immulite with Vidas for Detection of Infection in a Low-Prevalence Population of Pregnant Women in The Netherlands
Author(s) -
F. Vlaspolder,
Pamela Singer,
Andries J. Smit,
R. J. A. Diepersloot
Publication year - 2001
Publication title -
clinical and diagnostic laboratory immunology
Language(s) - English
Resource type - Journals
eISSN - 1098-6588
pISSN - 1071-412X
DOI - 10.1128/cdli.8.3.552-555.2001
Subject(s) - medicine , rubella , antibody , obstetrics , population , immunology , pediatrics , virology , gynecology , vaccination , measles , environmental health
A comparative evaluation of the Vidas system (bioMérieux, Marcy l'Etoile, France) and the Immulite System (Diagnostic Products Corporation) was performed using 500 prospectively collected serum samples. As part of a routine antenatal screening program, these samples were tested for hepatitis B surface antigen, and immunoglobulin G (IgG) and IgM antibodies to Toxoplasma gondii and rubella virus. The overall agreement between the two assay systems ranged from 98.0 to 99.8%. After discrepancy analysis the outcome in terms of relative sensitivity and specificity varied from 97.5 to 100%.