Comparison of Immulite with Vidas for Detection of Infection in a Low-Prevalence Population of Pregnant Women in The Netherlands | Zendy

F. Vlaspolder | Zendy; Pamela Singer | Zendy; Andries J. Smit | Zendy; R. J. A. Diepersloot | Zendy

Open Access

Comparison of Immulite with Vidas for Detection of Infection in a Low-Prevalence Population of Pregnant Women in The Netherlands

Author(s) -

F. Vlaspolder,

Pamela Singer,

Andries J. Smit,

R. J. A. Diepersloot

Publication year - 2001

Publication title -

clinical and diagnostic laboratory immunology

Language(s) - English

Resource type - Journals

eISSN - 1098-6588

pISSN - 1071-412X

DOI - 10.1128/cdli.8.3.552-555.2001

Subject(s) - medicine , rubella , antibody , obstetrics , population , immunology , pediatrics , virology , gynecology , vaccination , measles , environmental health

A comparative evaluation of the Vidas system (bioMérieux, Marcy l'Etoile, France) and the Immulite System (Diagnostic Products Corporation) was performed using 500 prospectively collected serum samples. As part of a routine antenatal screening program, these samples were tested for hepatitis B surface antigen, and immunoglobulin G (IgG) and IgM antibodies to Toxoplasma gondii and rubella virus. The overall agreement between the two assay systems ranged from 98.0 to 99.8%. After discrepancy analysis the outcome in terms of relative sensitivity and specificity varied from 97.5 to 100%.

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