Declining Immunoglobulin A Production in Prostates of Men with AIDS
Author(s) -
Henry J. Carson,
Nathan Lueck
Publication year - 1999
Publication title -
clinical and diagnostic laboratory immunology
Language(s) - English
Resource type - Journals
eISSN - 1098-6588
pISSN - 1071-412X
DOI - 10.1128/cdli.6.6.981-982.1999
Subject(s) - immunoperoxidase , immunoglobulin a , antibody , prostate , secretory iga , human immunodeficiency virus (hiv) , medicine , immunology , immunoglobulin g , cancer , monoclonal antibody
We studied immunoglobulin A production (IgA) in prostates of men with AIDS. Prostate sections from AIDS patients and human immunodeficiency virus-negative men were stained for IgA with immunoperoxidase. Prostate sections from nondiseased men were positive for IgA, while prostate sections from AIDS patients were essentially negative for IgA. Diminishing secretory IgA production may represent a characteristic of AIDS.
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