Primary Epitopes of Chicken Egg Yolk Antibodies to Peptidophosphogalactomannan | Zendy

Brigitte A. Tuekam | Zendy; Sandra J. Bonetti | Zendy; J.E. Gander | Zendy

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Primary Epitopes of Chicken Egg Yolk Antibodies to Peptidophosphogalactomannan

Author(s) -

Brigitte A. Tuekam,

Sandra J. Bonetti,

J.E. Gander

Publication year - 1998

Publication title -

clinical and diagnostic laboratory immunology

Language(s) - English

Resource type - Journals

eISSN - 1098-6588

pISSN - 1071-412X

DOI - 10.1128/cdli.5.3.404-406.1998

Subject(s) - epitope , yolk , antibody , phosphocholine , hapten , chemistry , biology , biochemistry , microbiology and biotechnology , food science , immunology , phospholipid , membrane , phosphatidylcholine

Egg yolks from hens immunized with peptidophosphogalactomannan (pPGalManii ), which contains 10 phosphocholine diester residues and is secreted byPenicillium fellutanum , contain antibodies against 5-O -β-d -galactofuranosyl epitopes. These epitopes were the only significant determinants in pPGalManii . Approximately 60-fold less pPGalManii (1.6 μM galactofuran chains) was required for 50% inhibition than galactofurano-oligosaccharides or pPGalMan containing two galactofuranosyl residues per chain.

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