Use of trans -Sialidase Inhibition Assay in a Population Serologically Negative for Trypanosoma cruzi but at a High Risk of Infection | Zendy

María Susana Leguizamón | Zendy; Graciela Russomando | Zendy; Antonieta Rojas de Árias | Zendy; Margarita Samudio | Zendy; Margarita Cabral | Zendy; Stella Maris González-Cappa | Zendy; Alberto C.C. Frasch | Zendy; Oscar Campetella | Zendy

Open Access

Use of trans -Sialidase Inhibition Assay in a Population Serologically Negative for Trypanosoma cruzi but at a High Risk of Infection

Author(s) -

María Susana Leguizamón,

Graciela Russomando,

Antonieta Rojas de Árias,

Margarita Samudio,

Margarita Cabral,

Stella Maris González-Cappa,

Alberto C.C. Frasch,

Oscar Campetella

Publication year - 1998

Publication title -

clinical and diagnostic laboratory immunology

Language(s) - English

Resource type - Journals

eISSN - 1098-6588

pISSN - 1071-412X

DOI - 10.1128/cdli.5.2.254-255.1998

Subject(s) - trypanosoma cruzi , serology , chagas disease , biology , virology , population , immunology , microbiology and biotechnology , medicine , parasite hosting , antibody , environmental health , world wide web , computer science

trans -Sialidase inhibition assay (TIA) was employed in a population at high risk ofTrypanosoma cruzi infection. From 20 serum samples that were negative by conventional serologic and parasitologic assays, 18 (90%) were reactive in TIA, providing further evidence of the higher sensitivity of TIA and suggesting that the actual prevalence ofT. cruzi infection might be underestimated.

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