Elevated Fecal Candida Counts in Patients with Antibiotic-Associated Diarrhea: Role of Soluble Fecal Substances
Author(s) -
Robert Krause,
Günter J. Krejs,
Christoph Wenisch,
Emil C. Reisinger
Publication year - 2003
Publication title -
clinical and vaccine immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.649
H-Index - 77
eISSN - 1556-6811
pISSN - 1556-679X
DOI - 10.1128/cdli.10.1.167-168.2003
Subject(s) - feces , candida albicans , diarrhea , antibiotics , microbiology and biotechnology , antibiotic associated diarrhea , biology , saline , gastroenterology , medicine , clostridium difficile
To assess the role of soluble fecal substances in the elevation of fecal Candida counts in patients with antibiotic-associated diarrhea (AAD), we investigated the growth of Candida albicans in vitro in serially diluted stool fluids from patients with AAD and healthy subjects. There were significantly higher Candida albicans counts in stool fluids diluted 1:10 from AAD patients than in healthy subjects and the phosphate-buffered saline growth control, which may be due to reduced soluble Candida inhibitors and increased availability of growth factors and nutrients.
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