Open AccessComplement-Fixing Antigens Produced by Varicella-Zoster Virus in Tissue Culture
Author(s) -
M. L. Martin,
E. L. Palmer
Publication year - 1973
Publication title -
applied microbiology
Language(s) - English
Resource type - Journals
ISSN - 0003-6919
DOI - 10.1128/am.26.3.410-413.1973
Subject(s) - antigen , virology , varicella zoster virus , complement (music) , virus , biology , pan t antigens , tissue culture , antibody , immunology , in vitro , phenotype , biochemistry , gene , complementation , monoclonal antibody
The complement-fixing antigens present in tissue cultures infected with varicella-zoster virus were separated into four components. There were (i) a cell-free soluble antigen, (ii) a cell-associated soluble antigen, (iii) a cell membrane-associated antigen, and (iv) a virion antigen. All four antigens were reactive with sera from patients with varicella or zoster, and about 90% of the total complement-fixing activity was found to be nonvirion associated.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom