Fluorescent-Antibody Reagent for the Identification of Cryptococcus neoformans | Zendy

Vern Pidcoe | Zendy; Leo Kaufman | Zendy

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Fluorescent-Antibody Reagent for the Identification of Cryptococcus neoformans

Author(s) -

Vern Pidcoe,

Leo Kaufman

Publication year - 1968

Publication title -

applied microbiology

Language(s) - English

Resource type - Journals

ISSN - 0003-6919

DOI - 10.1128/am.16.2.271-275.1968

Subject(s) - cryptococcus neoformans , conjugate , microbiology and biotechnology , cryptococcus , antiserum , cryptococcosis , antibody , biology , fluorescence , chemistry , virology , immunology , mathematical analysis , mathematics , physics , quantum mechanics

A sensitive and diagnostically applicable conjugate for the rapid and accurate detection and identification ofCryptococcus neoformans has been developed.C. neoformans rabbit antisera were produced by 14 daily intravenous injections of 36 million cells for a total dosage of approximately 500 million cells. Cross-staining reactions with species ofCryptococcus other thanC. neoformans , as well as withCandida species, were eliminated by adsorption of theC. neoformans conjugate with cells ofC. diffluens andC. krusei .

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