Open AccessMembrane Proteins and Proteomics of Cronobacter sakazakii Cells: Reliable Method for Identification and Subcellular Localization
Author(s) -
Jiří Novotný,
Barbora Svobodová,
Jiří Šantrůček,
L. Fukal,
Ludmila Karamonová
Publication year - 2022
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02508-21
Subject(s) - cronobacter sakazakii , cronobacter , proteome , biology , virulence , microbiology and biotechnology , bacterial outer membrane , proteomics , uniprot , computational biology , infant formula , biochemistry , enterobacter , escherichia coli , gene
Cronobacter spp. are opportunistic pathogens that can cause rare and, in many cases, life-threatening infections, such as meningitis, necrotizing enterocolitis, and sepsis. Such infections are mainly linked to the consumption of contaminated powdered infant formula, withCronobacter sakazakii clonal complex 4 considered the most frequent agent of serious neonatal infection.