Open AccessRational Regulation of Reaction Specificity of Nitrilase for Efficient Biosynthesis of 2-Chloronicotinic Acid through a Single Site Mutation
Author(s) -
Andi Dai,
Xiaoling Tang,
ZheMing Wu,
Jiang-Tao Tang,
RenChao Zheng,
YuGuo Zheng
Publication year - 2022
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.02397-21
Subject(s) - nitrilase , chemistry , biocatalysis , hydrolysis , steric effects , catalysis , stereochemistry , active site , combinatorial chemistry , reaction mechanism , organic chemistry
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