High-Level Production of Isoleucine and Fusel Alcohol by Expression of the Feedback Inhibition-Insensitive Threonine Deaminase in Saccharomyces cerevisiae | Zendy

Shota Isogai | Zendy; Akira Nishimura | Zendy; Atsushi Kotaka | Zendy; Naoyuki Murakami | Zendy; Natsuki Hotta | Zendy; Hiroki Ishida | Zendy; Hiroshi Takagi | Zendy

Open Access

High-Level Production of Isoleucine and Fusel Alcohol by Expression of the Feedback Inhibition-Insensitive Threonine Deaminase in Saccharomyces cerevisiae

Author(s) -

Shota Isogai,

Akira Nishimura,

Atsushi Kotaka,

Naoyuki Murakami,

Natsuki Hotta,

Hiroki Ishida,

Hiroshi Takagi

Publication year - 2022

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.02130-21

Subject(s) - fusel alcohol , saccharomyces cerevisiae , threonine , isoleucine , biochemistry , chemistry , biology , alcohol , leucine , enzyme , amino acid , yeast , serine

Fruit-like flavors of isoleucine-derived volatile compounds, 2-methyl-1-butanol (2MB) and its acetate ester, contribute to a variety of the flavors and tastes of alcoholic beverages. Besides its value as aroma components in foods and cosmetics, 2MB has attracted significant attention as second-generation biofuels.

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