MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b | Zendy

Philip Dershwitz | Zendy; Wenyu Gu | Zendy; Julien Roche | Zendy; Christina S. Kang-Yun | Zendy; Jeremy D. Semrau | Zendy; Thomas A. Bobik | Zendy; Bruce Fulton | Zendy; Hans Zischka | Zendy; Alan A. DiSpirito | Zendy

Open Access

MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b

Author(s) -

Philip Dershwitz,

Wenyu Gu,

Julien Roche,

Christina S. Kang-Yun,

Jeremy D. Semrau,

Thomas A. Bobik,

Bruce Fulton,

Hans Zischka,

Alan A. DiSpirito

Publication year - 2021

Publication title -

applied and environmental microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.552

H-Index - 324

eISSN - 1070-6291

pISSN - 0099-2240

DOI - 10.1128/aem.01841-21

Subject(s) - chemistry , oxazolone , thioamide , dipeptide , mutant , stereochemistry , operon , biochemistry , gene , peptide

A number of environmental and medical applications have been proposed for MBs, including bioremediation of toxic metals and nanoparticle formation, as well as the treatment of copper- and iron-related diseases. However, before MBs can be modified and optimized for any specific application, the biosynthetic pathway for MB production must be defined.

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