Open AccessA Single Nucleotide Change in the polC DNA Polymerase III in Clostridium thermocellum Is Sufficient To Create a Hypermutator Phenotype
Author(s) -
Anthony A. Lanahan,
Kamila Zakowicz,
Lei Tian,
Daniel G. Olson,
Lee R. Lynd
Publication year - 2022
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.01531-21
Subject(s) - clostridium thermocellum , cellulosic ethanol , biology , mutation , mutant , biochemistry , chemistry , cellulase , microbiology and biotechnology , genetics , cellulose , gene
Cellulosic biofuels are a promising approach to decarbonize the heavy-duty-transportation sector. A longstanding barrier to cost-effective cellulosic biofuel production is the recalcitrance of the material to solubilization.