Open AccessHeterologous Lactate Synthesis in Synechocystis sp. Strain PCC 6803 Causes a Growth Condition-Dependent Carbon Sink Effect
Author(s) -
Marcel Grund,
Torsten Jakob,
Jörg Toepel,
Andreas Schmid,
Christian Wilhelm,
Bruno Bühler
Publication year - 2022
Publication title -
applied and environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.552
H-Index - 324
eISSN - 1070-6291
pISSN - 0099-2240
DOI - 10.1128/aem.00063-22
Subject(s) - photosynthesis , carbon sink , sink (geography) , carbon fixation , cyanobacteria , chemistry , carbon assimilation , carbon source , carbon fibers , biochemistry , environmental chemistry , biology , ecology , materials science , ecosystem , bacteria , genetics , composite number , composite material , cartography , geography
Previous studies reported various and differing effects of the heterologous production of carbon-based molecules on photosynthetic and growth efficiency of cyanobacteria. The typically applied cultivation in batch mode, with continuously changing growth conditions, however, precludes a clear differentiation between the impact of cultivation conditions on cell physiology and effects related to the specific nature of the product and its synthesis pathway.