Open AccessComparative In Vitro Activities of Ertapenem (MK-0826) against 1,001 Anaerobes Isolated from Human Intra-Abdominal Infections
Author(s) -
Ellie J. C. Goldstein,
Diane M. Citron,
C. Vreni Merriam,
Yumi A. Warren,
Kerin L. Tyrrell
Publication year - 2000
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.44.9.2389-2394.2000
Subject(s) - ertapenem , bacteroides fragilis , microbiology and biotechnology , agar dilution method , agar dilution , bacteroides , biology , in vitro , agar , bacteria , antimicrobial , antibiotics , imipenem , minimum inhibitory concentration , antibiotic resistance , biochemistry , genetics
By using an agar dilution method, the comparative in vitro activities of ertapenem (MK-0826) were studied against 1,001 anaerobes isolated from human intra-abdominal infections in 17 countries worldwide. MK-0826 was uniformly active against all isolates, including allBacteroides fragilis group species isolates, with the exception of 12 of 61 (20%) strains ofBilophila wadsworthia , 3 strains of lactobacilli, and 1 isolate ofAcidaminococcus fermentans . Geographical variation in activity was not observed.