Open AccessIn Vitro Activities of Sitafloxacin (DU-6859a) and Six Other Fluoroquinolones against 8,796 Clinical Bacterial Isolates
Author(s) -
Danica Milatovic,
FranzJosef Schmitz,
Sylvain Brisse,
J. Verhoef,
Ad C. Fluit
Publication year - 2000
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.44.4.1102-1107.2000
Subject(s) - trovafloxacin , gatifloxacin , moxifloxacin , microbiology and biotechnology , ciprofloxacin , levofloxacin , peptostreptococcus , ofloxacin , antibacterial agent , gram positive cocci , anaerobic bacteria , biology , bacteria , staphylococcus aureus , antibiotics , genetics
The in vitro activities of sitafloxacin, ciprofloxacin, trovafloxacin, levofloxacin, clinafloxacin, gatifloxacin, and moxifloxacin against 5,046 gram-negative bacteria, 3,344 gram-positive cocci, and 406 anaerobes were determined. Sitafloxacin was the most active agent against gram-positive cocci and anaerobes. AgainstEnterobacteriaceae and nonfermenters, its activity was either equivalent to or better than that of clinafloxacin.