Open AccessComparative In Vitro Activities of Ciprofloxacin, Gemifloxacin, Grepafloxacin, Moxifloxacin, Ofloxacin, Sparfloxacin, Trovafloxacin, and Other Antimicrobial Agents against Bloodstream Isolates of Gram-Positive Cocci
Author(s) -
Dwight J. Hardy,
Daniel Amsterdam,
Lionel A. Mandell,
Coleman Rotstein
Publication year - 2000
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.44.3.802-805.2000
Subject(s) - gemifloxacin , trovafloxacin , microbiology and biotechnology , moxifloxacin , sparfloxacin , antimicrobial , ofloxacin , levofloxacin , ciprofloxacin , streptococcus pneumoniae , penicillin , antibacterial agent , biology , antibiotics
The in vitro activity of gemifloxacin against 316 bloodstream isolates of staphylococci, pneumococci, and enterococci was compared with the activities of six fluoroquinolones and three other antimicrobial agents. Of the antimicrobial agents tested, gemifloxacin was the most potent against penicillin-intermediate and -resistant pneumococci, methicillin-susceptible and -resistantStaphylococcus epidermidis isolates, and coagulase-negative staphylococci.