Open AccessEfficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with Itraconazole Capsules
Author(s) -
Laura J. Cross,
Jeremy Bagg,
T. C. Aitchison
Publication year - 2000
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.44.2.425-427.2000
Subject(s) - itraconazole , stomatitis , capsule , cyclodextrin , pharmacology , antifungal , medicine , chemistry , chromatography , dermatology , biology , botany
This study investigated the efficacy of a cyclodextrin solution of itraconazole in the treatment ofCandida -associated denture stomatitis. It was found that the liquid and capsule preparations of itraconazole were equally effective adjuncts in the treatment of this condition. However, the side effect profile indicates that capsules are the preferred formulation.