Bactericidal Activity and Postantibiotic Effect of Levofloxacin against Anaerobes | Zendy

Susan L. Pendland | Zendy; Mariela DiazLinares | Zendy; Kevin W. Garey | Zendy; Jennifer G. Woodward | Zendy; Seon Young Ryu | Zendy; Larry H. Danziger | Zendy

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Bactericidal Activity and Postantibiotic Effect of Levofloxacin against Anaerobes

Author(s) -

Susan L. Pendland,

Mariela DiazLinares,

Kevin W. Garey,

Jennifer G. Woodward,

Seon Young Ryu,

Larry H. Danziger

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.10.2547

Subject(s) - levofloxacin , microbiology and biotechnology , minimum inhibitory concentration , antibacterial agent , minimum bactericidal concentration , chemistry , biology , antimicrobial , antibiotics

The bactericidal activity and postantibiotic effect (PAE) of levofloxacin against nine anaerobes were determined. Levofloxacin at concentrations of the MIC and twice the MIC was bactericidal at 24 h to five of nine and nine of nine strains, respectively. The PAE of levofloxacin following a 2-h exposure ranged from 0.06 to 2.88 h.

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