Prevalence of Antimicrobial Resistance in Respiratory Tract Isolates of Streptococcus pneumoniae : Results of a Canadian National Surveillance Study | Zendy

George G. Zhanel | Zendy; James A. Karlowsky | Zendy; Lorraine Palatnick | Zendy; Lavern M. Vercaigne | Zendy; Donald E. Low | Zendy; Daryl J. Hoban | Zendy

Open Access

Prevalence of Antimicrobial Resistance in Respiratory Tract Isolates of Streptococcus pneumoniae : Results of a Canadian National Surveillance Study

Author(s) -

George G. Zhanel,

James A. Karlowsky,

Lorraine Palatnick,

Lavern M. Vercaigne,

Donald E. Low,

Daryl J. Hoban

Publication year - 1999

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.43.10.2504

Subject(s) - streptococcus pneumoniae , microbiology and biotechnology , sulfamethoxazole , penicillin , trimethoprim , respiratory tract infections , antimicrobial , tetracycline , antibiotic resistance , respiratory tract , medicine , pneumococcal infections , antibiotics , biology , respiratory system

From October 1997 to November 1998, 1,180 respiratory tract isolates ofStreptococcus pneumoniae were collected from 18 medical centers in 9 of the 10 Canadian provinces. Penicillin-intermediate and -resistant isolates occurred at rates of 14.8 and 6.4%, respectively, and these rates varied considerably by geographic region. Trimethoprim-sulfamethoxazole, tetracycline, and macrolide rates of nonsusceptibility were 12.2, 10.6, and 8.0 to 9.3%, respectively. The most potent agents studied were newer fluoroquinolones.

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