Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages | Zendy

N Mor | Zendy; A Esfandiari | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages

Author(s) -

N Mor,

A Esfandiari

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.9.2035

Subject(s) - clarithromycin , pyrazinamide , mycobacterium tuberculosis , microbiology and biotechnology , tuberculosis , antibacterial agent , medicine , ethambutol , pharmacology , mycobacterium , antibiotics , biology , pathology

The combination of clarithromycin and pyrazinamide was found to be synergistic against Mycobacterium tuberculosis in human macrophages. MICs were four- to eightfold lower for this combination than they were for either drug alone. Clarithromycin and rifampin, however, had only an additive effect.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research