In vitro activity of trovafloxacin against Chlamydia pneumoniae | Zendy

P M Roblin | Zendy; Andrei Kutlin | Zendy; M R Hammerschlag | Zendy

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In vitro activity of trovafloxacin against Chlamydia pneumoniae

Author(s) -

P M Roblin,

Andrei Kutlin,

M R Hammerschlag

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.9.2033

Subject(s) - trovafloxacin , ofloxacin , microbiology and biotechnology , chlamydia , doxycycline , azithromycin , erythromycin , antibacterial agent , ciprofloxacin , in vitro , antibiotics , pharmacology , biology , chemistry , immunology , biochemistry

The in vitro susceptibilities of 12 strains of Chlamydia pneumoniae to a new quinolone, trovafloxacin, and ofloxacin, doxycycline, erythromycin, and azithromycin were determined. The activity of trovafloxacin was similar to that of ofloxacin, with a MIC at which 90% of the isolates are inhibited and a minimal concentration at which 90% of the isolates are killed of 1.0 microg/ml, but trovafloxacin was less active than doxycycline, erythromycin, and azithromycin.

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