In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species | Zendy

José A. Vázquez | Zendy; Maria Lynch | Zendy; Dina Boikov | Zendy; J. D. Sobel | Zendy

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In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species

Author(s) -

José A. Vázquez,

Maria Lynch,

Dina Boikov,

J. D. Sobel

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.7.1612

Subject(s) - azole , microbiology and biotechnology , candida albicans , candida glabrata , candida krusei , biology , candida parapsilosis , in vitro , candida tropicalis , corpus albicans , antifungal , fluconazole , biochemistry

The in vitro activity of a new pneumocandin, L-743,872, was evaluated with 108 strains of Candida and compared with the activities of various antifungals. L-743,872 demonstrated the best activity against azole-susceptible and -resistant strains of C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, and C. kefyr and less activity against C. krusei, C. lusitaniae, and C. guilliermondii.

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