In vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary importance | Zendy

Jeffrey L. Watts | Zendy; Sarah A. Salmon | Zendy; M. S. Sanchez | Zendy; Robert J. Yancey | Zendy

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In vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary importance

Author(s) -

Jeffrey L. Watts,

Sarah A. Salmon,

M. S. Sanchez,

Robert J. Yancey

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.5.1190

Subject(s) - danofloxacin , enrofloxacin , ciprofloxacin , microbiology and biotechnology , antimicrobial , bacilli , biology , veterinary medicine , quinolone , in vitro , antibiotics , medicine , bacteria , biochemistry , genetics

The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active (MIC for 90% of the strains tested [MIC90], 0.015 to 0.25 microg/ml) than the comparison antimicrobial agents (MIC90, 0.13 to 16.0 microg/ml) against the staphylococci, streptococci, and anaerobes tested.

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