Open AccessIn vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary importance
Author(s) -
Jeffrey L. Watts,
Sarah A. Salmon,
M S Sanchez,
Robert J. Yancey
Publication year - 1997
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.41.5.1190
Subject(s) - danofloxacin , enrofloxacin , ciprofloxacin , microbiology and biotechnology , antimicrobial , bacilli , biology , veterinary medicine , quinolone , in vitro , antibiotics , medicine , bacteria , biochemistry , genetics
The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active (MIC for 90% of the strains tested [MIC90], 0.015 to 0.25 microg/ml) than the comparison antimicrobial agents (MIC90, 0.13 to 16.0 microg/ml) against the staphylococci, streptococci, and anaerobes tested.