Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing | Zendy

David M. Bamberger | Zendy; Betty Herndon | Zendy; Mary Amanda Dew | Zendy; RS Chern | Zendy; H. M. Mitchell | Zendy; Lisa Summers | Zendy; R F Marcus | Zendy; S C Kim | Zendy; R. Padma Suvarna | Zendy

Open Access

Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing

Author(s) -

David M. Bamberger,

Betty Herndon,

Mary Amanda Dew,

RS Chern,

H. M. Mitchell,

Lisa Summers,

R F Marcus,

S C Kim,

R. Padma Suvarna

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.5.1178

Subject(s) - ofloxacin , clindamycin , microbiology and biotechnology , staphylococcus aureus , antimicrobial , intracellular , antibiotics , antibacterial agent , biology , bacteria , ciprofloxacin , genetics

We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay. Ofloxacin plus rifampin was the most effective regimen in the abscess model, and rifampin and ofloxacin were the most active regimens in the intracellular killing assay.

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