In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica | Zendy

Kristı́n Ingólfsdóttir | Zendy; Martha Á. Hjálmarsdóttir | Zendy; Albert P. Sigurdsson | Zendy; Guðbjört Guðjónsdóttir | Zendy; Ása Brynjólfsdóttir | Zendy; Ólafur Steingrı́msson | Zendy

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In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica

Author(s) -

Kristı́n Ingólfsdóttir,

Martha Á. Hjálmarsdóttir,

Albert P. Sigurdsson,

Guðbjört Guðjónsdóttir,

Ása Brynjólfsdóttir,

Ólafur Steingrı́msson

Publication year - 1997

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.41.1.215

Subject(s) - lichen , helicobacter pylori , in vitro , biology , moss , microbiology and biotechnology , methylene blue , botany , biochemistry , photocatalysis , genetics , catalysis

With reference to the traditional use of Cetraria islandica (Iceland moss) for relief of gastric and duodenal ulcer, plant extracts were screened for in vitro activity against Helicobacter pylori. (+)-Protolichesterinic acid, an aliphatic alpha-methylene-gamma-lactone, was identified as an active component. The MIC range of protolichesterinic acid, in free as well as salt form, was 16 to 64 micrograms/ml.

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