In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria | Zendy

Hannah M. Wexler | Zendy; E Molitoris | Zendy; D. Molitoris | Zendy; S M Finegold | Zendy

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In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria

Author(s) -

Hannah M. Wexler,

E Molitoris,

D. Molitoris,

S M Finegold

Publication year - 1996

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.40.9.2232

Subject(s) - bacteroides fragilis , trovafloxacin , microbiology and biotechnology , peptostreptococcus , anaerobic bacteria , agar dilution , prevotella , fusobacterium , clostridium , biology , veillonella , bacteroides , bacteria , antibacterial agent , chemistry , antimicrobial , antibiotics , streptococcus , minimum inhibitory concentration , genetics

The antimicrobial activity of trovafloxacin for 557 strains of anaerobic bacteria was determined by the National Committee for Clinical Laboratory Standards-approved Wadsworth agar dilution technique. The species tested included Bacteroides fragilis (n = 91), other members of the B. fragilis group (n = 130), Campylobacter gracilis (n = 15), other Bacteroides spp. (n = 16), Prevotella spp. (n = 49), Porphyromonas spp. (n = 15), Fusobacterium spp. (n = 62), Bilophila wadsworthia (n = 24), Sutterella wadsworthensis (n = 21), Clostridium spp. (n = 61), Peptostreptococcus spp. (n = 38), and gram-positive non-spore-forming rods (n = 35). Trovafloxacin inhibited all strains of B. fragilis at < or = 0.5 microgram/ml, 99% of other B. fragilis group species at < or = 2 micrograms/ml, and 96% of all anaerobes tested at < or = 2 micrograms/ml.

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