Antimicrobial susceptibilities of Campylobacter jejuni and Campylobacter coli to 12 beta-lactam agents and combinations with beta-lactamase inhibitors | Zendy

Pilar Tajada | Zendy; J L Gomez-Graces | Zendy; Juan-Ignacio Alós | Zendy; D Balas | Zendy; R Cogollos | Zendy

Open Access

Antimicrobial susceptibilities of Campylobacter jejuni and Campylobacter coli to 12 beta-lactam agents and combinations with beta-lactamase inhibitors

Author(s) -

Pilar Tajada,

J L Gomez-Graces,

Juan-Ignacio Alós,

D Balas,

R Cogollos

Publication year - 1996

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.40.8.1924

Subject(s) - campylobacter jejuni , clavulanic acid , cefotaxime , imipenem , campylobacter , microbiology and biotechnology , ampicillin , cefepime , amoxicillin , beta lactamase , campylobacter coli , antibacterial agent , antimicrobial , beta lactamase inhibitors , biology , antibiotics , bacteria , antibiotic resistance , escherichia coli , biochemistry , genetics , gene

The in vitro activities of 12 beta-lactam agents against 100 thermophilic Campylobacter strains were tested. Beta-Lactamase production was detected in 88% of all strains tested. Clavulanic acid was the best inhibitor by susceptibility testing. The beta-lactams which displayed high levels of in vitro activity against Campylobacter isolates were imipenem, amoxicillin-clavulanic acid, and cefepime and, to a lesser degree, amoxicillin, ampicillin, and cefotaxime.

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