Open AccessNovel method for assessing postantibiotic effect by using the Coulter counter
Author(s) -
R C Li,
S W Lee,
Joyce S.Y. Lam
Publication year - 1996
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.40.7.1751
Subject(s) - coulter counter , serial dilution , sample (material) , chromatography , chemistry , biology , medicine , pathology , alternative medicine , microbiology and biotechnology
To study postantibiotic effect, viable counts are routinely acquired by the pour plate technique. However, this technique is laborious and time-consuming; the required sample dilutions also cause excessive errors and material wastage. A new total cell counting technique in which a Coulter counter is used to obtain more efficient postantibiotic effect measurements has been developed.
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