In vitro susceptibilities of clinical and environmental isolates of Cryptococcus neoformans to five antifungal drugs | Zendy

Sarah P. Franzot | Zendy; Júnia Soares Hamdan | Zendy

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In vitro susceptibilities of clinical and environmental isolates of Cryptococcus neoformans to five antifungal drugs

Author(s) -

Sarah P. Franzot,

Júnia Soares Hamdan

Publication year - 1996

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.40.3.822

Subject(s) - cryptococcus neoformans , flucytosine , itraconazole , fluconazole , ketoconazole , amphotericin b , cryptococcosis , microbiology and biotechnology , biology , cryptococcus , antifungal

A total of 53 Cryptococcus neoformans strains, including clinical and environmental Brazilian isolates, were tested for their susceptibilities to amphotericin B, 5-flucytosine, ketoconazole, fluconazole, and itraconazole. The tests were performed according to the National Committee of Clinical Laboratory Standards recommendations (document M27-P). In general, there was a remarkable homogeneity of results for all strains, and comparable MICs were found for environmental and clinical isolates. This paper represents the first contribution in which susceptibility data for Brazilian C. neoformans isolates are provided.

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