Emergence of fluoroquinolone-resistant Escherichia coli in fecal flora of cancer patients receiving norfloxacin prophylaxis | Zendy

Jordi Carratalà | Zendy; A. FernándezSevilla | Zendy; Fé Tubau | Zendy; M.Á. Domínguez | Zendy; Francesc Gudiol | Zendy

Open Access

Emergence of fluoroquinolone-resistant Escherichia coli in fecal flora of cancer patients receiving norfloxacin prophylaxis

Author(s) -

Jordi Carratalà,

A. FernándezSevilla,

Fé Tubau,

M.Á. Domínguez,

Francesc Gudiol

Publication year - 1996

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.40.2.503

Subject(s) - norfloxacin , escherichia coli , feces , bacteremia , medicine , microbiology and biotechnology , ciprofloxacin , antibiotics , gastroenterology , biology , biochemistry , gene

We studied 122 stool samples collected from 25 patients with hematologic malignancies who received prophylactic norfloxacin. Fecal samples were obtained at admission and twice weekly thereafter during prophylaxis. Fluoroquinolone-resistant Escherichia coli strains were isolated from the feces of 10 (40%) of the patients; two patients had fluoroquinolone-resistant E. coli strains prior to beginning norfloxacin treatment, and in the other eight patients, the strains appeared subsequently. One patient developed fluoroquinolone-resistant E. coli bacteremia after 10 days of norfloxacin administration.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research