Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates | Zendy

A Ohlin | Zendy; H Hoover-Litty | Zendy; G Sanderson | Zendy; A. Paessens | Zendy; Sebastian L. Johnston | Zendy; Stephen T. Holgate | Zendy; E D Huguenel | Zendy; J M Greve | Zendy

Open Access

Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates

Author(s) -

A Ohlin,

H Hoover-Litty,

G Sanderson,

A. Paessens,

Sebastian L. Johnston,

Stephen T. Holgate,

E D Huguenel,

J M Greve

Publication year - 1994

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.38.6.1413

Subject(s) - rhinovirus , intercellular adhesion molecule 1 , microbiology and biotechnology , serotype , broad spectrum , biology , intracellular , adhesion , in vitro , virology , chemistry , biochemistry , virus , organic chemistry , combinatorial chemistry

The antiviral potency of soluble intercellular adhesion molecule-1 (ICAM-1; the major receptor for human rhinoviruses) was determined for a subset of American Type Culture Collection reference serotypes and field isolates of rhinovirus. The results indicate that soluble ICAM-1 exhibits a broad spectrum of activity against rhinoviruses and that field isolates have a sensitivity indistinguishable from that of laboratory strains.

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