Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid | Zendy

Collin D. Freeman | Zendy; C H Nightingale | Zendy; David P. Nicolau | Zendy; Paul Belliveau | Zendy; Mary Anné Banevicius | Zendy; Richard Quintiliani | Zendy

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Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid

Author(s) -

Collin D. Freeman,

C H Nightingale,

David P. Nicolau,

Paul Belliveau,

Mary Anné Banevicius,

Richard Quintiliani

Publication year - 1994

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.38.10.2449

Subject(s) - azithromycin , penetration (warfare) , extracellular , extracellular fluid , intracellular , medicine , chemistry , immunology , microbiology and biotechnology , antibiotics , biology , biochemistry , operations research , engineering

The penetration of azithromycin into the blister fluids of six volunteers was analyzed after a 5-day regimen (total of 1.5 g). Differences in drug concentrations in a paper disk and serum and in the mass of azithromycin from inflammatory blister chamber leukocytes and noninflammatory blister chamber leukocytes were significant (P < 0.05).

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