Resistance of Peptostreptococcus spp. to macrolides and lincosamides: inducible and constitutive phenotypes | Zendy

Milagro Reig | Zendy; A. Vives Moreno | Zendy; Fernando Baquero | Zendy

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Resistance of Peptostreptococcus spp. to macrolides and lincosamides: inducible and constitutive phenotypes

Author(s) -

Milagro Reig,

A. Vives Moreno,

Fernando Baquero

Publication year - 1992

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.36.3.662

Subject(s) - lincosamides , peptostreptococcus , erythromycin , microbiology and biotechnology , clindamycin , biology , tylosin , antibiotics , bacteria , genetics , bacteroides

The activities of erythromycin and clindamycin against 350 Peptostreptococcus strains were studied during a 5-year period (1986 to 1991). In 5.1% of the Peptostreptococcus strains, which presented dissociated resistance (clindamycin MIC, less than or equal to 1 microgram/ml; erythromycin MIC, greater than 8 micrograms/ml), evidence of inducible macrolide-lincosamide resistance was shown. A total of 17.7% of the strains presented a constitutive phenotype; the clindamycin and erythromycin MICs for these strains were greater than 8 micrograms/ml.

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