Open AccessResistance of Peptostreptococcus spp. to macrolides and lincosamides: inducible and constitutive phenotypes
Author(s) -
Milagro Reig,
A. Vives Moreno,
Fernando Baquero
Publication year - 1992
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.36.3.662
Subject(s) - lincosamides , peptostreptococcus , erythromycin , microbiology and biotechnology , clindamycin , biology , tylosin , antibiotics , bacteria , genetics , bacteroides
The activities of erythromycin and clindamycin against 350 Peptostreptococcus strains were studied during a 5-year period (1986 to 1991). In 5.1% of the Peptostreptococcus strains, which presented dissociated resistance (clindamycin MIC, less than or equal to 1 microgram/ml; erythromycin MIC, greater than 8 micrograms/ml), evidence of inducible macrolide-lincosamide resistance was shown. A total of 17.7% of the strains presented a constitutive phenotype; the clindamycin and erythromycin MICs for these strains were greater than 8 micrograms/ml.